Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815387 | 0.81 | SIRT5 (0.59) | HPGDALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8814545 | 0.80 | SIRT5 (0.57) | HPGDALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2924409 | 0.74 | HPGD (0.73) | HPGDALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9478637 | 0.71 | ALPG (0.69) | HPGDALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL7046987 | 0.70 | ALDH1A1 (0.72) | HPGDALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3657544 | 0.70 | HPGD (0.51) | HPGDALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8815070 | 0.69 | MEN1 (0.46) | ALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL209681 | 0.69 | POLB (0.49) | HPGDALDH1A1KMT2ATDP1GAA | |
| SCHEMBL8814996 | 0.69 | KMT2A (0.59) | HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL7441888 | 0.68 | ITGB3 (0.54) | HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |