Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15137506 | 0.95 | POLB (0.32) | APEX1SMN1; SMN2GAAPOLBRORC | |
| SCHEMBL15417350 | 0.93 | PKM (0.34) | APEX1SMN1; SMN2ALDH1A1TBXA2RPKM | |
| SCHEMBL15417320 | 0.92 | ALDH1A1 (0.34) | GAAALDH1A1MAPK1 | |
| SCHEMBL1714643 | 0.92 | POLB (0.34) | APEX1SMN1; SMN2POLBALDH1A1TBXA2R | |
| SCHEMBL23724052 | 0.88 | APEX1 (0.36) | APEX1SMN1; SMN2GAAPOLBALDH1A1 | |
| SCHEMBL1065475 | 0.88 | APEX1 (0.36) | APEX1SMN1; SMN2GAAPOLBALDH1A1 | |
| Bromide SCHEMBL861823 | 0.87 | APEX1 (0.35) | APEX1SMN1; SMN2GAAPOLBALDH1A1 | |
| SCHEMBL1067864 | 0.87 | APEX1 (0.35) | APEX1SMN1; SMN2GAAPOLBALDH1A1 | |
| SCHEMBL2535520 | 0.87 | CYP3A4 (0.31) | — | |
| SCHEMBL997083 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040108-A2 | MULTIVALENT FLUORESCENT PROBES | CALIPER LIFE SCIENCES (US) | 2012-03-29 | — | — | WO | disclosed |