SCHEMBL8814733

SCHEMBL8814733

CC1(C)C(=O)N(c2ccccc2)C(=O)N1CCCCl

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.46
HTR1A P08908 2/20 0.46
HTR7 P34969 2/20 0.46
HTR6 P50406 2/20 0.46
ELANE P08246 4/20 0.45
TAS2R8 Q9NYW2 4/20 0.43
PGR P06401 1/20 0.41
IGF1R P08069 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153535 0.76 ELANE (0.47) ARELANETAS2R8PGRIGF1R
SCHEMBL16841781 0.75 AR (0.61) ARPGR
SCHEMBL13803703 0.75 ELANE (0.46) ARELANETAS2R8PGRIGF1R
SCHEMBL13039129 0.74 IGF1R (0.67) TAS2R8IGF1R
SCHEMBL19923441 0.71 GRM4 (0.57) ARELANEPGR
SCHEMBL8030958 0.70 ELANE (0.46) ARELANETAS2R8IGF1R
SCHEMBL4032680 0.69 PGR (0.81) ARPGR
SCHEMBL11654508 0.68 PGR (0.58) ELANEPGR
SCHEMBL8023307 0.68 TAS2R8 (0.47) ELANETAS2R8IGF1R
SCHEMBL634929 0.68 AR (0.48) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9031060-A None JP disclosed
JP-H0931060-A PRODUCTION OF CYCLIC UREA COMPOUND NISSAN CHEM IND LTD 1997-02-04 JP disclosed