Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628333 | 0.87 | HDAC1 (0.58) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL12628340 | 0.86 | HDAC1 (0.57) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL11045005 | 0.85 | HDAC1 (0.48) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL22432716 | 0.84 | HRH3 (0.60) | ADRB3ADRB2ADRB1ACHE | |
| Hydrochloric Acid SCHEMBL10636985 | 0.84 | HDAC1 (0.47) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL10636799 | 0.83 | SCN5A (0.50) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL3085320 | 0.82 | GAA (0.70) | SIGMAR1ALDH1A1GAAALOX15TSHR | |
| SCHEMBL16494639 | 0.82 | ACHE (0.62) | HDAC1HDAC6ADRB3ADRB2ADRB1 | |
| SCHEMBL16494539 | 0.82 | ACHE (0.59) | HDAC1HDAC6ACHE | |
| SCHEMBL16494249 | 0.82 | ACHE (0.55) | HDAC1HDAC6ALDH1A1ACHEMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9278752-A | — | — | None | — | — | JP | disclosed |
| EP-2394990-A1 | INDOLINE DERIVATIVES | Kyoto University (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110294850-A1 | INDOLINE DERIVATIVES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-12-01 | — | — | US | disclosed |
| JP-H09278752-A | PRODUCTION OF 5-METHOXYINDOLINE DERIVATIVE | IHARA CHEM IND CO LTD | 1997-10-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294850-A1 | INDOLINE DERIVATIVES | BCHE, ACHE, INMT | HDAC1 154/4885HDAC6 472/4885ADRB3 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.