Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12488574 | 0.84 | MAOB (0.46) | MAOAMAOB | |
| SCHEMBL23940770 | 0.79 | AKR1B1 (0.51) | MAOAMAOBDRD2HTR7ANPEP | |
| SCHEMBL30859067 | 0.79 | MAOA (0.55) | MAOAMAOBHTR7PRCPTHRB | |
| SCHEMBL149766 | 0.79 | MAOA (0.55) | MAOAMAOBHTR7PRCPTHRB | |
| SCHEMBL2492866 | 0.78 | AHR (0.45) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| Xanthene SCHEMBL20969988 | 0.78 | MAOA (0.81) | MAOAMAOB | |
| SCHEMBL13777196 | 0.78 | MAOA (0.73) | MAOAMAOB | |
| SCHEMBL29680062 | 0.78 | AHR (0.45) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL28967142 | 0.77 | MAOA (0.53) | MAOAMAOBHTR7PRCPTHRB | |
| Xanthene SCHEMBL4451064 | 0.76 | MAOA (0.85) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |