Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13648824 | 0.88 | ADORA2A (0.34) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL881719 | 0.84 | PTGS2 (0.30) | — | |
| SCHEMBL881453 | 0.84 | POLRMT (0.34) | STING1ACVRL1 | |
| SCHEMBL24699893 | 0.84 | PIK3CD (0.32) | ADORA2AACVRL1 | |
| SCHEMBL10187245 | 0.81 | NPC1 (0.36) | STING1 | |
| SCHEMBL882142 | 0.81 | KDM4E (0.31) | — | |
| SCHEMBL881381 | 0.80 | ADORA2A (0.40) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10149698 | 0.80 | ADORA2A (0.40) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL881709 | 0.79 | PTGS2 (0.36) | — | |
| SCHEMBL15682919 | 0.77 | ADORA2A (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |