Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.43 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | RAD1 | O60671 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819088 | 0.82 | CA2 (0.47) | ALDH1A1MEN1MAPTKMT2ACDC25B | |
| SCHEMBL110924 | 0.79 | SENP2 (0.60) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL110923 | 0.79 | SENP2 (0.60) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL13578938 | 0.79 | SENP2 (0.56) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL2622737 | 0.79 | SENP2 (0.56) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL1436156 | 0.79 | SENP2 (0.60) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL31099405 | 0.79 | SENP2 (0.60) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL19050353 | 0.78 | RAD1 (0.40) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL11320660 | 0.78 | HSD17B10 (0.46) | NQO1RAD1P2RY6ALDH1A1MEN1 | |
| SCHEMBL24712520 | 0.78 | SENP2 (0.47) | SENP2SENP1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| US-20120130068-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| EP-1514905-B1 | High light fastness reactive red dyes | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130068-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | DPYD, NQO1, MT-ND5 | SENP2 4755/4885SENP1 4785/4885SUMO2 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.