Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062005 | 0.79 | LMNA (0.57) | ALDH1A1GLAKDM4ETDP1MAPT | |
| SCHEMBL6608661 | 0.77 | HTR7 (0.52) | ALDH1A1KDM4ECYP1A2MAPTL3MBTL1 | |
| SCHEMBL1592876 | 0.77 | TDP1 (0.60) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL30463519 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL2090885 | 0.75 | ALDH1A1 (0.53) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL254578 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL11679951 | 0.75 | CYP2D6 (0.61) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL9808080 | 0.75 | ALDH1A1 (0.62) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL13360698 | 0.74 | KDM4E (0.70) | ALDH1A1KDM4ECYP1A2SCN4AMAPT | |
| SCHEMBL25210036 | 0.73 | SCN4A (0.53) | ALDH1A1GLAKDM4ECYP1A2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |