Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068124 | 0.77 | MKNK2 (0.42) | MKNK2MKNK1EGFRADORA2AADORA1 | |
| SCHEMBL13195335 | 0.75 | MKNK2 (0.40) | MKNK2MKNK1EGFRADORA2BADORA2A | |
| SCHEMBL326707 | 0.75 | MTNR1A (0.48) | SLC2A1ALDH1A1 | |
| SCHEMBL25818492 | 0.75 | MKNK2 (0.40) | MKNK2MKNK1EGFRPRMT5WDR77 | |
| SCHEMBL2173797 | 0.75 | MKNK2 (0.40) | MKNK2MKNK1EGFRPRMT5WDR77 | |
| SCHEMBL18926936 | 0.73 | MKNK2 (0.39) | MKNK2MKNK1SLC2A1ADORA2BADORA3 | |
| Ammonia Solution, Strong SCHEMBL27463691 | 0.72 | PI4KA (0.39) | MKNK2MKNK1PRMT5WDR77ALDH1A1 | |
| SCHEMBL1079073 | 0.71 | FDPS (0.50) | HPGDNPC1RAB9ASMN1; SMN2ADORA2B | |
| SCHEMBL25301570 | 0.71 | HTR2C (0.52) | — | |
| SCHEMBL24110604 | 0.71 | HTR2C (0.47) | MKNK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032879-A1 | 7-ALKYL-PYRROLO[2,3-d]PYRIMIDINES | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |