Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | FADS1 | O60427 | 2/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814916 | 0.84 | L3MBTL1 (0.80) | ALDH1A1SMN1; SMN2MEN1KMT2AKDR | |
| SCHEMBL6779138 | 0.79 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTL3MBTL1CHRNB2 | |
| SCHEMBL15778718 | 0.77 | FADS1 (0.74) | ALDH1A1SMN1; SMN2FADS1GRM4HDAC6 | |
| SCHEMBL4981491 | 0.77 | KDR (0.72) | SMN1; SMN2FADS1KDR | |
| SCHEMBL4017821 | 0.76 | KDR (0.77) | ALDH1A1SMN1; SMN2FADS1GRM4HDAC6 | |
| SCHEMBL2701738 | 0.76 | FADS1 (1.00) | ALDH1A1FADS1MEN1KMT2AP2RX1 | |
| SCHEMBL29496401 | 0.76 | GRM4 (1.00) | SMN1; SMN2GRM4HDAC6KDRNPC1 | |
| SCHEMBL2530324 | 0.76 | GRM4 (1.00) | SMN1; SMN2GRM4HDAC6KDRNPC1 | |
| SCHEMBL16007625 | 0.75 | MEN1 (0.76) | ALDH1A1SMN1; SMN2FADS1GRM4HDAC6 | |
| SCHEMBL20772457 | 0.75 | MAPT (0.62) | ALDH1A1MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804420-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |