Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817725 | 0.84 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12900891 | 0.81 | L3MBTL1 (0.84) | L3MBTL1ALDH1A1KMT2AMEN1KCNK3 | |
| SCHEMBL259421 | 0.79 | KCNK3 (0.86) | ALDH1A1KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL6779138 | 0.79 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL533767 | 0.77 | KCNK3 (0.81) | L3MBTL1ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL4978310 | 0.77 | KDR (0.71) | L3MBTL1ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL10063193 | 0.77 | ITK (0.62) | L3MBTL1ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL16454855 | 0.77 | PIK3CD (0.50) | L3MBTL1ALDH1A1KMT2AMEN1PKM | |
| SCHEMBL12812751 | 0.76 | MEN1 (0.68) | L3MBTL1ALDH1A1KMT2AMEN1KCNK3 | |
| SCHEMBL22573826 | 0.76 | KCNK3 (0.53) | L3MBTL1ALDH1A1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804420-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |