Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133156 | 0.83 | SMN1; SMN2 (0.43) | SLC15A1LTA4HLAP3ANPEPSMN1; SMN2 | |
| SCHEMBL10700924 | 0.83 | LTA4H (0.45) | LTA4HSMN1; SMN2HIF1AALDH1A1SLC7A5 | |
| SCHEMBL7258076 | 0.79 | TSHR (0.48) | LTA4HCTSLSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL4061223 | 0.78 | SIRT2 (0.44) | ALDH1A1 | |
| SCHEMBL28962790 | 0.78 | ALDH1A1 (0.47) | SLC15A1LTA4HLAP3ANPEPSMN1; SMN2 | |
| SCHEMBL4161005 | 0.77 | IDO1 (0.53) | SLC15A1LTA4HLAP3ANPEPALDH1A1 | |
| SCHEMBL10441465 | 0.77 | IDO1 (0.53) | SLC15A1LTA4HLAP3ANPEPALDH1A1 | |
| SCHEMBL10421087 | 0.77 | SLC1A1 (0.46) | SLC15A1LTA4HSMN1; SMN2HIF1AALPI | |
| SCHEMBL11011081 | 0.76 | LTA4H (0.50) | SLC15A1LTA4HSMN1; SMN2HIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28986973 | 0.76 | IDO1 (0.52) | SLC15A1LTA4HLAP3ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016410-A1 | NOVEL INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | claimed |
| WO-1997016410-A1 | NOVEL INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |