Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311383 | 0.83 | LMNA (0.38) | ELANEF2CTSGCMA1CTRC | |
| SCHEMBL13879504 | 0.83 | ELANE (0.47) | ELANEMGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL10575698 | 0.82 | GAA (0.50) | MGLLCACNA1BAPBA1GAAMEN1 | |
| SCHEMBL8726554 | 0.80 | MGLL (0.53) | ELANEMGLLRAB9AMAPTGAA | |
| SCHEMBL4632378 | 0.79 | ALDH1A1 (0.37) | RAB9AMAPTGAAMEN1KMT2A | |
| SCHEMBL10480512 | 0.78 | KMT2A (0.38) | KMT2AALDH1A1 | |
| SCHEMBL6480244 | 0.78 | SCN2A (0.49) | RAB9AMAPTGAAMEN1KMT2A | |
| SCHEMBL1979602 | 0.76 | LMNA (0.52) | MGLLMAPTTP53ALDH1A1MAPK1 | |
| SCHEMBL30939548 | 0.76 | LMNA (0.52) | MGLLMAPTTP53ALDH1A1MAPK1 | |
| SCHEMBL13198797 | 0.75 | RAB9A (0.66) | ELANEF2CTSGCMA1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038303-A1 | METHOD AND SYSTEM FOR IDENTIFICATION, PURIFICATION, AND QUANTITATION OF REACTION COMPONENTS | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | disclosed |
| US-5670054-A | AUTOMATIC | WARNER LAMBERT COMPANY (US) | 1997-09-23 | — | — | US | disclosed |