Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 8/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817544 | 0.85 | MGAM (0.50) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL8818574 | 0.84 | GAA (0.64) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL9259477 | 0.79 | MAPT (0.54) | GAAPARP1MAPT | |
| SCHEMBL8817053 | 0.77 | DHODH (0.65) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL7146754 | 0.74 | DHODH (0.62) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL8891044 | 0.73 | MGAM (0.68) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL31027957 | 0.73 | DHODH (0.59) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL10385941 | 0.72 | DHODH (0.52) | GAADHODHPARP1TP53MAPT | |
| SCHEMBL18347676 | 0.71 | PARP1 (0.54) | GAADHODHPARP1MAPTRPS6KA3 | |
| SCHEMBL252964 | 0.70 | MAPK13 (0.85) | MGAMGAATP53MAPTMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |