Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | NT5E | P21589 | 5/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820284 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7627010 | 0.84 | ADORA3 (0.60) | ADORA3NT5EADORA1ADORA2A | |
| SCHEMBL7627041 | 0.84 | ADORA3 (0.60) | ADORA3NT5EADORA1ADORA2A | |
| SCHEMBL8819182 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9404051 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL24601162 | 0.80 | ALDH1A1 (0.70) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8819416 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8820548 | 0.78 | ADORA1 (0.70) | ADORA3ADORA1ADORA2A | |
| SCHEMBL8820317 | 0.78 | ALDH1A1 (0.67) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8820534 | 0.78 | ADORA1 (0.70) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033590-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |