Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.58 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.58 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.58 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.58 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272421 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL8817717 | 0.85 | HDAC4 (0.59) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL196689 | 0.84 | CYP1A1 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL29589241 | 0.84 | CYP1A1 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL13069497 | 0.83 | ACHE (0.52) | CYP1A2CYP3A4CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL6285490 | 0.82 | CRHR1 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL21480791 | 0.82 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2A6 | |
| SCHEMBL11281941 | 0.81 | HTR7 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19CYP1A1 | |
| SCHEMBL29973127 | 0.80 | MEN1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL1528920 | 0.80 | CD274 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455370-A1 | PHARMACEUTICAL PRODUCT CONTAINING LACTAM OR BENZENE SULFONAMIDE COMPOUND | Shionogi&Co., Ltd. (JP) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007819-A1 | PHARMACEUTICAL PRODUCT CONTAINING LACTAM OR BENZENE SULFONAMIDE COMPOUND | 塩野義製薬株式会社 (JP) | 2011-01-20 | — | — | WO | disclosed |