Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696307 | 0.74 | ALDH1A1 (0.43) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL1741537 | 0.74 | PLA2G2A (0.52) | FFAR4ALDH1A1MAPTTSHRPLA2G2A | |
| SCHEMBL12489097 | 0.70 | FFAR4 (0.47) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8891670 | 0.70 | PLA2G2A (0.50) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL16958853 | 0.69 | SLC6A4 (0.49) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL364074 | 0.68 | FFAR4 (0.48) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7703503 | 0.68 | FFAR4 (0.45) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8747754 | 0.67 | KMT2A (0.43) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL22827958 | 0.67 | CA1 (0.45) | FFAR4ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL21180877 | 0.67 | ALDH1A1 (0.45) | FFAR4ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046207-A2 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-11 | — | — | WO | disclosed |