Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859749 | 0.89 | HTR6 (0.45) | HTR6CCNT1CDK9HTR2CHTR2A | |
| SCHEMBL7867988 | 0.85 | DAO (0.37) | HTR6DAOHTR2CHTR2AMAPT | |
| SCHEMBL7876549 | 0.79 | SIGMAR1 (0.53) | HTR6DAOCCNT1CDK9HTR2C | |
| SCHEMBL5138986 | 0.77 | SIGMAR1 (0.51) | HTR6CCNT1CDK9HTR2CHTR2A | |
| SCHEMBL8019719 | 0.76 | MAPT (0.39) | HTR6HTR2CHTR2AMAPTKDM4E | |
| SCHEMBL7859769 | 0.75 | HTR6 (0.37) | HTR6HTR2CSIGMAR1QDPR | |
| SCHEMBL9974662 | 0.73 | HTR2C (0.59) | HTR6HTR2CSIGMAR1QDPR | |
| SCHEMBL7867959 | 0.72 | HTR6 (0.48) | HTR6DAOCCNT1CDK9HTR2C | |
| SCHEMBL6707999 | 0.71 | QDPR (0.49) | HTR6HTR2CMAPTKDM4EALDH1A1 | |
| SCHEMBL4568028 | 0.69 | NPC1 (0.58) | DAOMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |