Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140299 | 0.81 | GABRA1 (0.34) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL7854558 | 0.71 | SLC6A12 (0.35) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL7072429 | 0.65 | SLC6A12 (0.45) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL459030 | 0.61 | — | — | |
| SCHEMBL971678 | 0.61 | — | — | |
| SCHEMBL10296559 | 0.60 | — | — | |
| SCHEMBL92858 | 0.60 | KDM4E (0.43) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL22587458 | 0.60 | KDM4E (0.43) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| Hydrochloric Acid SCHEMBL10808909 | 0.60 | CHRNB2 (0.49) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL11579290 | 0.59 | TSHR (0.46) | GABRA1GABRA5GABRB2GABRA4SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047624-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1997047625-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |