Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 3/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764393 | 0.82 | KDM4E (0.59) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| Hydrochloric Acid SCHEMBL9764420 | 0.81 | NOS3 (0.59) | HSD17B10KDM4EALOX15HTR6 | |
| SCHEMBL6631360 | 0.78 | HTR6 (0.60) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL8558613 | 0.78 | HTR6 (0.65) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL5705100 | 0.74 | KDM4E (0.66) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL29379037 | 0.74 | KDM4E (1.00) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL653742 | 0.74 | KDM4E (1.00) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL13533314 | 0.73 | HTR6 (0.63) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL7392593 | 0.73 | JAK2 (0.69) | HSD17B10ALDH1A1KDM4EMAPTHTR2C | |
| SCHEMBL7487825 | 0.73 | HTR6 (0.51) | HSD17B10ALDH1A1KDM4EMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038692-A1 | BISINDOLES FOR TREATING PAIN OR NOCICEPTION | ELI LILLY AND COMPANY (US) | 1997-10-23 | — | — | WO | disclosed |