Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 9/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404051 | 0.92 | ALDH1A1 (0.51) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8819182 | 0.92 | ALDH1A1 (0.51) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8817593 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8327419 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL23436497 | 0.84 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL15679138 | 0.84 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8818839 | 0.84 | LMNA (0.69) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9080632 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL9404265 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8909878 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033591-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| US-5430027-A | 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias | NOVO NORDISK A/S (DK) | 1995-07-04 | — | — | US | disclosed |