Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819041 | 0.87 | HTT (0.40) | THRBTP53MAPTMEN1KMT2A | |
| SCHEMBL9819039 | 0.87 | HTT (0.40) | THRBTP53MAPTMEN1KMT2A | |
| SCHEMBL9818756 | 0.77 | HTT (0.42) | MEN1KMT2AMTNR1ATSHRSMN1; SMN2 | |
| SCHEMBL9818762 | 0.77 | HTT (0.42) | MEN1KMT2AMTNR1ATSHRSMN1; SMN2 | |
| SCHEMBL27865204 | 0.75 | HTT (0.39) | THRBTP53MAPTMEN1KMT2A | |
| SCHEMBL9819040 | 0.72 | LTB4R (0.43) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9819044 | 0.72 | LTB4R (0.43) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23423177 | 0.71 | KMT2A (0.43) | THRBTP53MAPTMEN1KMT2A | |
| SCHEMBL9818872 | 0.70 | ABCB1 (0.46) | MTNR1AHTTHPGD | |
| SCHEMBL9818878 | 0.70 | ABCB1 (0.46) | MTNR1AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997007120-A9 | BIPHENYL(THIO)AMIDE AND BIPHENYLETHAN(THI)ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS 5-HT1D RECEPTOR ANTAGONISTS | — | 1997-04-03 | — | — | WO | disclosed |