Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818878 | 1.00 | ABCB1 (0.46) | ABCB1HPGDAKR1B1HTTMTNR1A | |
| SCHEMBL9819044 | 0.86 | LTB4R (0.43) | ABCB1HPGDHTTPOLB | |
| SCHEMBL9819040 | 0.86 | LTB4R (0.43) | ABCB1HPGDHTTPOLB | |
| SCHEMBL9818756 | 0.85 | HTT (0.42) | HPGDAKR1B1HTTMTNR1AMTNR1B | |
| SCHEMBL9818762 | 0.85 | HTT (0.42) | HPGDAKR1B1HTTMTNR1AMTNR1B | |
| SCHEMBL9819041 | 0.82 | HTT (0.40) | HPGDAKR1B1HTTMTNR1APOLB | |
| SCHEMBL9819039 | 0.82 | HTT (0.40) | HPGDAKR1B1HTTMTNR1APOLB | |
| SCHEMBL9818900 | 0.79 | MAOB (0.41) | HTT | |
| SCHEMBL9818902 | 0.79 | MAOB (0.41) | HTT | |
| SCHEMBL9818765 | 0.76 | AKR1B1 (0.45) | ABCB1AKR1B1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |