Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780499 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPK10KDM4E | |
| SCHEMBL31305794 | 0.76 | ALDH1A1 (0.37) | ALDH1A1CA2CA1KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL6775496 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPK10KDM4E | |
| SCHEMBL8823260 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CA2CA1CA12CA9 | |
| SCHEMBL28380222 | 0.72 | FABP4 (0.50) | ALDH1A1LMNAADAMTS4KMT2AMAPK10 | |
| SCHEMBL2531253 | 0.67 | LMNA (0.68) | LMNAKMT2ANPSR1KDM4E | |
| SCHEMBL31020737 | 0.67 | ALDH1A1 (0.55) | ALDH1A1ADAMTS4CA2CA1CA12 | |
| SCHEMBL41618 | 0.65 | GAA (0.53) | ALDH1A1LMNAHTTKMT2AHSD17B10 | |
| SCHEMBL199861 | 0.65 | GAA (0.53) | ALDH1A1LMNAHTTKMT2AHSD17B10 | |
| SCHEMBL41619 | 0.65 | GAA (0.53) | ALDH1A1LMNAHTTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | claimed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | claimed |