SCHEMBL31020737

SCHEMBL31020737

C[C@H](Nc1ccc(S(C)(=O)=O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TGM2 P21980 1/20 0.47
CA2 P00918 5/20 0.47
CA1 P00915 4/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ADAMTS4 O75173 1/20 0.45
ITGB1 P05556 1/20 0.44
ITGA4 P13612 1/20 0.44
AKR1C3 P42330 2/20 0.44
AKR1C2 P52895 2/20 0.44
ENPP2 Q13822 1/20 0.44
PTGS2 P35354 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1988912 0.86 CA2 (0.47) ALDH1A1CA2CA1CA12CA9
SCHEMBL1988910 0.86 CA2 (0.47) ALDH1A1CA2CA1CA12CA9
SCHEMBL27999251 0.82 KEAP1 (0.52) ALDH1A1CA2CA1CA12CA9
SCHEMBL30644158 0.81 PKM (0.57) ALDH1A1CA2CA1CA12CA9
SCHEMBL28018549 0.80 ALDH1A1 (0.53) ALDH1A1CA2CA1CA12CA9
SCHEMBL2584998 0.79 TDP1 (0.54) ALDH1A1CA12CA9ADAMTS4
SCHEMBL13589509 0.79 TDP1 (0.48) ALDH1A1TGM2CA2CA1CA9
SCHEMBL8526966 0.78 ITGB1 (0.53) TGM2CA2CA1CA12CA9
SCHEMBL8527030 0.78 ITGB1 (0.53) TGM2CA2CA1CA12CA9
SCHEMBL14715693 0.78 ITGB1 (0.53) TGM2CA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113481228-B Microbial unnatural amino acid introducing system and construction method 中国药科大学 2024-07-19 CN claimed
CN-113481228-B Microbial unnatural amino acid introducing system and construction method 中国药科大学 2024-07-19 CN disclosed