Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 12/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247942 | 0.94 | PLA2G4B (0.57) | LTA4HPLA2G4BPLA2G4ATSHRRECQL | |
| SCHEMBL1743419 | 0.89 | PLA2G4B (0.57) | PLA2G4BPLA2G4ATSHRRECQL | |
| SCHEMBL8707397 | 0.87 | PLA2G4B (0.59) | PLA2G4BPLA2G4A | |
| SCHEMBL9650471 | 0.87 | PLA2G4B (0.59) | PLA2G4BPLA2G4A | |
| SCHEMBL12655267 | 0.83 | SMN1; SMN2 (0.63) | LTA4HSMN1; SMN2PLA2G4B | |
| SCHEMBL13545912 | 0.77 | LTA4H (1.00) | LTA4HSMN1; SMN2 | |
| SCHEMBL12250691 | 0.77 | KMT2A (0.61) | SMN1; SMN2PLA2G4B | |
| SCHEMBL13472198 | 0.77 | KMT2A (0.57) | SMN1; SMN2PLA2G4B | |
| Pentane SCHEMBL8673099 | 0.76 | ALOX15 (0.77) | LTA4HSMN1; SMN2PLA2G4BTSHRRECQL | |
| SCHEMBL8225239 | 0.76 | SMN1; SMN2 (0.67) | LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | claimed |