Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARS1 | P26639 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 5/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826640 | 0.92 | LMNA (0.45) | TARS1ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL5266256 | 0.90 | ALDH1A1 (0.45) | TARS1ALDH1A1HPGDLMNA | |
| SCHEMBL5385111 | 0.81 | LTA4H (0.48) | TARS1LTA4HNR1H2BAXMAOA | |
| SCHEMBL14366360 | 0.81 | LTA4H (0.48) | TARS1LTA4HNR1H2BAXMAOA | |
| SCHEMBL9487460 | 0.80 | LTA4H (0.52) | LTA4HNR1H2BAXMAOATSHR | |
| SCHEMBL6262545 | 0.79 | TAS1R3 (0.47) | MAOAPARP10ALDH1A1CA1CA2 | |
| SCHEMBL11272914 | 0.78 | LMNA (0.56) | LTA4HMAOAPARP10PPARGPPARA | |
| SCHEMBL22687549 | 0.78 | LTA4H (0.55) | LTA4HNR1H2BAXMAOATSHR | |
| Diphenylether SCHEMBL11134302 | 0.77 | LTA4H (0.67) | LTA4HNR1H2BAXMAOATSHR | |
| Diphenylether SCHEMBL29076650 | 0.77 | LTA4H (0.67) | LTA4HNR1H2BAXMAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |