SCHEMBL8823993

SCHEMBL8823993

IC(SOSC(I)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.36
TSHR P16473 2/20 0.36
F2 P00734 1/20 0.36
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP2D6 P10635 2/20 0.32
SRC P12931 1/20 0.32
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 2/20 0.31
HRH1 P35367 1/20 0.31
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31
GRM7 Q14831 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2874877 0.74 TSHR (0.43) DPP4TSHRF2HTR2ATAAR1
SCHEMBL9051939 0.72 DPP4 (0.38) DPP4TSHRF2HTR2ATAAR1
SCHEMBL913100 0.70 KMT2A (0.41) DPP4TSHRF2TAAR1CYP2D6
SCHEMBL11132156 0.70 DPP4 (0.48) DPP4F2HTR2ATAAR1LMNA
SCHEMBL28511593 0.70 DPP4 (0.36) DPP4TSHRF2HTR2ATAAR1
SCHEMBL3718532 0.70 LMNA (0.41) TSHRCYP2D6SRCLMNAMAPK1
SCHEMBL9281233 0.70 MIF (0.36) TAAR1CYP2D6KMT2ALMNA
SCHEMBL546542 0.67 KMT2A (0.38) DPP4TSHRF2HTR2ACYP2D6
SCHEMBL873428 0.66 DPP4 (0.47) DPP4TSHRF2HTR2ATAAR1
SCHEMBL11721312 0.66 DPP4 (0.47) DPP4TSHRF2HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684130-A Process for synthesis of organic compounds using magnetic particles SOLID PHASE SCIENCES CORPORATION (US) 1997-11-04 US disclosed