SCHEMBL3718532

SCHEMBL3718532

OC(SOSC(O)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
MAPK1 P28482 1/20 0.41
AOC3 Q16853 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP2D6 P10635 1/20 0.37
SRC P12931 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9712055 0.81 CHRM2 (0.42) LMNAMAPK1AOC3TSHRSMN1; SMN2
SCHEMBL3648024 0.76 ALDH1A1 (0.46) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL2874877 0.74 TSHR (0.43) TSHRL3MBTL1CYP2D6SRC
SCHEMBL9633963 0.74 TSHR (0.46) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL1268813 0.72 LMNA (0.46) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL22519675 0.72 LMNA (0.46) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL1719932 0.72 LMNA (0.42) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL28106402 0.70 LMNA (0.44) LMNAMAPK1AOC3TSHRKDM4E
SCHEMBL11132156 0.70 DPP4 (0.48) LMNAKDM4EADRA2AADRA2CHIF1A
SCHEMBL913100 0.70 KMT2A (0.41) LMNATSHRKDM4EL3MBTL1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406795-B Lubricating oil composition for spark-ignition internal combustion engine, process for producing the lubricating oil composition, spark-ignition internal combustion engine using the lubricating oil composition, and method for lubricating the internal combustion engine 出光兴产株式会社 2021-08-17 CN claimed
CN-104530417-B A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2017-09-08 CN claimed
CN-104530415-B A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance 厦门赛诺邦格生物科技股份有限公司 2017-09-01 CN claimed
CN-104530415-A Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof XIAMEN SINOPEG BIOTECH INC 2015-04-22 CN claimed
CN-104530417-A Multifunctional H-type polyethylene glycol derivative and preparation method thereof XIAMEN SINOPEG BIOTECH INC 2015-04-22 CN claimed
CN-104109235-A Mono-functionalized polyethylene glycol with nitrogen atom branched center and its preparation method and biologically-relevant matter XIAMEN SINOPEG BIOTECH CO LTD 2014-10-22 CN claimed
CN-104725628-B A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group 厦门赛诺邦格生物科技股份有限公司 2018-04-17 CN disclosed
CN-104530417-B A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2017-09-08 CN disclosed
CN-104530415-B A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance 厦门赛诺邦格生物科技股份有限公司 2017-09-01 CN disclosed
CN-104530413-B A kind of bio-related substance of multiple functionalized H types polyethyleneglycol derivative modification 厦门赛诺邦格生物科技股份有限公司 2017-08-25 CN disclosed
CN-104109235-B A kind of single functionalized poly (ethylene glycol), preparation method and its bio-related substance with nitrogen-atoms branch centers 厦门赛诺邦格生物科技股份有限公司 2017-07-18 CN disclosed
CN-104725628-A Single functional branched polyethylene glycol containing degradable radical, preparation method and biorelevant substance of single functional branched polyethylene glycol XIAMEN SINOPEG BIOTECH CO LTD 2015-06-24 CN disclosed
CN-104530417-A Multifunctional H-type polyethylene glycol derivative and preparation method thereof XIAMEN SINOPEG BIOTECH INC 2015-04-22 CN disclosed
US-20090326145-A1 S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers BASF SE (DE) 2009-12-31 US disclosed
US-20090326145-A1 S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers BASF SE (DE) 2009-12-31 US disclosed
EP-2027202-B1 S-PERFLUOROALKYL SUBSTITUTED HYDROXYBENZYLTHIOETHERS AND DERIVATIVES AS SURFACE MODIFIERS BASF SE (DE) 2009-08-12 EP disclosed
CN-101466782-A S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers CIBA HOLDING INC (CH) 2009-06-24 CN disclosed
CN-101466782-A S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers CIBA HOLDING INC (CH) 2009-06-24 CN disclosed
EP-2027202-A1 S-PERFLUOROALKYL SUBSTITUTED HYDROXYBENZYLTHIOETHERS AND DERIVATIVES AS SURFACE MODIFIERS Ciba Holding Inc. (CH) 2009-02-25 EP disclosed
WO-2007144283-A1 S-PERFLUOROALKYL SUBSTITUTED HYDROXYBENZYLTHIOETHERS AND DERIVATIVES AS SURFACE MODIFIERS CIBA HOLDING INC. (CH) 2007-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326145-A1 S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers HBS1L, SGMS1, SULT1A1 LMNA 1840/4885MAPK1 2111/4885AOC3 2279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.