Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825493 | 0.91 | PPARG (0.54) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL8825377 | 0.87 | CYSLTR2 (0.49) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL8825418 | 0.83 | PPARG (0.41) | PPARGPPARALTB4R | |
| SCHEMBL8825101 | 0.83 | MAPT (0.39) | PPARGPPARALTB4RLMNAMAPT | |
| SCHEMBL8825187 | 0.79 | CYSLTR2 (0.51) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL8825193 | 0.74 | LTB4R (0.45) | PPARGPPARACYSLTR2CYSLTR1LTB4R | |
| SCHEMBL8825203 | 0.74 | ALOX15 (0.36) | — | |
| SCHEMBL8977815 | 0.73 | CYSLTR1 (0.45) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL8977829 | 0.73 | CYSLTR2 (0.45) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL8825269 | 0.72 | PTPN11 (0.41) | CYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |