Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825860 | 0.85 | DNMT1 (0.33) | HPGDMAPTMLYCDDNMT1ALDH1A1 | |
| SCHEMBL8826071 | 0.84 | MAPT (0.35) | MAPTKMT2ALMNAHTTMEN1 | |
| SCHEMBL8825920 | 0.84 | ALDH1A1 (0.32) | HPGDMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8825870 | 0.83 | PTGIR (0.39) | HPGDMAPTALDH1A1LMNANPC1 | |
| SCHEMBL8826142 | 0.79 | MAPT (0.35) | HPGDMAPTMLYCDALDH1A1KMT2A | |
| SCHEMBL11152924 | 0.79 | MEN1 (0.43) | HPGDMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8826056 | 0.78 | HPGD (0.35) | HPGDMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8826171 | 0.76 | KIF11 (0.34) | HPGDMAPTMLYCDALDH1A1KMT2A | |
| SCHEMBL8826138 | 0.70 | MAPT (0.33) | HPGDMAPTDNMT1ALDH1A1KMT2A | |
| SCHEMBL8826068 | 0.69 | MAPT (0.35) | MAPTALDH1A1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |