Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825867 | 0.86 | CA1 (0.39) | PTGIRCA1CA2LMNACA12 | |
| SCHEMBL8825865 | 0.83 | HPGD (0.34) | LMNAMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL8826071 | 0.81 | MAPT (0.35) | LMNACYP1A2MAPTNPSR1RECQL | |
| SCHEMBL8825920 | 0.81 | ALDH1A1 (0.32) | MAPTALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL8826137 | 0.81 | NR1I2 (0.40) | PTGIRCA1CA2LMNACA12 | |
| SCHEMBL8825935 | 0.80 | PTGIR (0.36) | PTGIRCA1CA2LMNACA12 | |
| SCHEMBL8826033 | 0.77 | KIF11 (0.39) | PTGIRCA1CA2LMNACES2 | |
| SCHEMBL11152924 | 0.76 | MEN1 (0.43) | CA1CA2LMNACES1MAPT | |
| SCHEMBL8825863 | 0.74 | MAPT (0.45) | CA1CA2LMNACA12CA7 | |
| SCHEMBL8826132 | 0.72 | APP (0.37) | PTGIRCA1CA2LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |