Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825917 | 0.85 | MAPT (0.32) | HPGDMAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8825865 | 0.84 | HPGD (0.34) | ALDH1A1HPGDTSHRMAPTMEN1 | |
| SCHEMBL8826071 | 0.82 | MAPT (0.35) | POLBTSHRHSD17B10MAPTMEN1 | |
| SCHEMBL8825870 | 0.81 | PTGIR (0.39) | ALDH1A1HPGDALOX15MAPK1HSD17B10 | |
| SCHEMBL8825740 | 0.79 | KCNH2 (0.35) | ALDH1A1HPGDPOLBTSHRFFAR1 | |
| SCHEMBL8826064 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2GAA | |
| SCHEMBL11152924 | 0.77 | MEN1 (0.43) | ALDH1A1HPGDPOLBMAPK1HSD17B10 | |
| SCHEMBL8826154 | 0.76 | KCNN4 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL3887649 | 0.72 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1TSHRHSD17B10 | |
| SCHEMBL562612 | 0.71 | ALDH1A1 (0.54) | ALDH1A1ALOX15MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |