Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NPY2R | P49146 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | ADK | P55263 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990561 | 0.89 | LMNA (0.68) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL8826256 | 0.86 | ADORA3 (0.66) | SMN1; SMN2NPC1RAB9ASLC29A1TSHR | |
| SCHEMBL8826282 | 0.85 | CYP1A2 (0.47) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL8826176 | 0.84 | ADORA3 (0.57) | SLC29A1 | |
| SCHEMBL9360359 | 0.84 | ADORA3 (0.57) | SLC29A1 | |
| SCHEMBL8939236 | 0.82 | TSHR (0.59) | PMP22SMN1; SMN2HTTSLC29A1RXFP1 | |
| SCHEMBL8826179 | 0.81 | SLC29A1 (0.56) | SLC29A1TSHRNFKB1THPO | |
| SCHEMBL8826350 | 0.81 | SLC29A1 (0.51) | SLC29A1 | |
| SCHEMBL5199003 | 0.80 | HIF1A (0.56) | — | |
| SCHEMBL5198998 | 0.80 | HIF1A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |