Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
| ▸ | PGK2 | P07205 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826379 | 0.89 | TDP1 (0.50) | ADORA3ADORA1ADORA2AADORA2BCDK1 | |
| SCHEMBL8826282 | 0.87 | CYP1A2 (0.47) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL8826256 | 0.86 | ADORA3 (0.66) | ADORA3ADORA1ADORA2ASLC29A1TP53 | |
| SCHEMBL8826210 | 0.86 | PGK1 (0.56) | ADORA3ADORA1TP53PGK1PGK2 | |
| SCHEMBL8826529 | 0.84 | PGK1 (0.50) | ADORA3ADORA1TP53PGK1PGK2 | |
| SCHEMBL8826235 | 0.84 | PGK1 (0.55) | ADORA3ADORA1ADORA2BSLC29A1TP53 | |
| SCHEMBL9542046 | 0.84 | ADORA3 (0.63) | ADORA3ADORA1ADORA2BTP53PGK1 | |
| SCHEMBL8826290 | 0.84 | ADORA3 (0.63) | ADORA3ADORA1ADORA2BTP53PGK1 | |
| SCHEMBL8826299 | 0.83 | PGK1 (0.49) | ADORA3ADORA1TP53PGK1PGK2 | |
| SCHEMBL9356875 | 0.83 | PGK1 (0.49) | ADORA3ADORA1TP53PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |