Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.55 |
| ▸ | PGK2 | P07205 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826544 | 0.93 | PGK1 (0.56) | PGK1PGK2ADORA3ADORA1ADORA2B | |
| SCHEMBL8826210 | 0.92 | PGK1 (0.56) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL8826290 | 0.88 | ADORA3 (0.63) | PGK1PGK2ADORA3ADORA1ADORA2B | |
| SCHEMBL9542046 | 0.88 | ADORA3 (0.63) | PGK1PGK2ADORA3ADORA1ADORA2B | |
| SCHEMBL8826529 | 0.86 | PGK1 (0.50) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL9356875 | 0.86 | PGK1 (0.49) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL8826299 | 0.86 | PGK1 (0.49) | PGK1PGK2ADORA3ADORA1PNP | |
| SCHEMBL8826179 | 0.85 | SLC29A1 (0.56) | ADORA3ADORA1SLC29A1 | |
| SCHEMBL8830311 | 0.84 | NR1I2 (0.60) | PDE4D | |
| SCHEMBL8826175 | 0.84 | ADORA3 (0.53) | PGK1PGK2ADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |