Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356771 | 0.88 | ADORA1 (0.51) | CYP1A2LMNASMN1; SMN2HTTRXFP1 | |
| SCHEMBL8826259 | 0.88 | ADORA1 (0.51) | CYP1A2LMNASMN1; SMN2HTTRXFP1 | |
| SCHEMBL8826175 | 0.87 | ADORA3 (0.53) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL8826218 | 0.85 | LMNA (0.64) | CYP1A2LMNATHPOCYP2C19SMN1; SMN2 | |
| SCHEMBL9542046 | 0.85 | ADORA3 (0.63) | CYP1A2LMNASMN1; SMN2HTTRXFP1 | |
| SCHEMBL8826290 | 0.85 | ADORA3 (0.63) | CYP1A2LMNASMN1; SMN2HTTRXFP1 | |
| SCHEMBL8826210 | 0.83 | PGK1 (0.56) | CYP1A2LMNASMN1; SMN2HTTRXFP1 | |
| SCHEMBL8830311 | 0.83 | NR1I2 (0.60) | PDE4D | |
| SCHEMBL8826529 | 0.82 | PGK1 (0.50) | LMNASMN1; SMN2HTTRXFP1ADORA3 | |
| SCHEMBL8826235 | 0.82 | PGK1 (0.55) | CYP1A2LMNASMN1; SMN2HTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |