Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15499073 | 0.89 | NR1I2 (0.61) | NR1I2ALBPDE4DABCB1 | |
| SCHEMBL8826290 | 0.88 | ADORA3 (0.63) | PDE4D | |
| SCHEMBL9542046 | 0.88 | ADORA3 (0.63) | PDE4D | |
| SCHEMBL8826529 | 0.86 | PGK1 (0.50) | NR1I2ALBPDE4D | |
| SCHEMBL8826210 | 0.86 | PGK1 (0.56) | PDE4D | |
| SCHEMBL8939236 | 0.85 | TSHR (0.59) | — | |
| SCHEMBL8826235 | 0.84 | PGK1 (0.55) | PDE4D | |
| SCHEMBL9150000 | 0.84 | PDE4D (0.61) | PDE4D | |
| SCHEMBL8826299 | 0.83 | PGK1 (0.49) | PDE4D | |
| SCHEMBL8826282 | 0.83 | CYP1A2 (0.47) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637574-A | VIRICIDES | GLAXO WELLCOME INC. (US) | 1997-06-10 | — | — | US | claimed |
| EP-0620734-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-10-26 | — | — | EP | claimed |
| WO-1993013778-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| US-5637574-A | VIRICIDES | GLAXO WELLCOME INC. (US) | 1997-06-10 | — | — | US | disclosed |