Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808029 | 0.87 | PTPN1 (0.37) | ALKALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL8827945 | 0.76 | ESR1 (0.40) | ALDH1A1SMN1; SMN2HPGDHSD17B10MAPT | |
| SCHEMBL8828015 | 0.75 | KMT2A (0.41) | ADRA2AADRA2BADRA2CALDH1A1SMN1; SMN2 | |
| SCHEMBL8827914 | 0.72 | ALDH1A1 (0.38) | ALKALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL27919055 | 0.70 | MAPT (0.61) | ALKALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8680387 | 0.68 | MAPT (0.56) | ALKALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL8808018 | 0.68 | ESR1 (0.61) | ALDH1A1HSD17B10KDM4ETSHRMAPT | |
| SCHEMBL8827929 | 0.68 | GRIA1 (0.39) | ALKALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL8676997 | 0.65 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDHSD17B10KDM4E | |
| SCHEMBL12854117 | 0.65 | RAB9A (0.54) | ALDH1A1SMN1; SMN2HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672609-A | POSTMENOPAUSAL SYNDROME; ANTILIPEMIC AND -CARCINOGENIC AGENTS; OSTEOPOROSIS; CARDIOTONIC AGENTS; RESTENOSIS; SIDE EFFECT REDUCTION COMPARED TO ESTROGEN | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | claimed |