Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828451 | 0.87 | DRD2 (0.45) | DRD3DRD2ALDH1A1KMT2ADRD4 | |
| SCHEMBL8828348 | 0.84 | BRD9 (0.40) | DRD3DRD2ALDH1A1DRD4NCF1 | |
| SCHEMBL8828572 | 0.81 | ADRB1 (0.49) | DRD3DRD2ALDH1A1KMT2AHTR7 | |
| Sifaprazine SCHEMBL21524898 | 0.77 | NCF1 (0.58) | DRD3DRD2ALDH1A1MEN1KMT2A | |
| SCHEMBL8828393 | 0.77 | HSD17B10 (0.55) | DRD3DRD2ALDH1A1MEN1KMT2A | |
| Sifaprazine SCHEMBL9656921 | 0.76 | NCF1 (0.56) | DRD3DRD2ALDH1A1MEN1KMT2A | |
| SCHEMBL27413682 | 0.76 | DRD2 (0.56) | DRD3DRD2ALDH1A1MEN1KMT2A | |
| SCHEMBL4249373 | 0.75 | TSHR (0.56) | DRD3DRD2ALDH1A1MEN1KMT2A | |
| SCHEMBL2172785 | 0.75 | HRH1 (0.47) | DRD3DRD2MEN1KMT2ADRD4 | |
| SCHEMBL8828453 | 0.74 | DRD4 (0.46) | DRD3DRD2ALDH1A1DRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |