Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828451 | 0.91 | DRD2 (0.45) | BRD9NCF1SNCADRD2HTR1A | |
| SCHEMBL8828381 | 0.84 | DRD3 (0.38) | NCF1SNCADRD2DRD4DRD3 | |
| SCHEMBL8828572 | 0.81 | ADRB1 (0.49) | DRD2DRD3ALDH1A1LMNA | |
| SCHEMBL8828393 | 0.80 | HSD17B10 (0.55) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL13061367 | 0.79 | NCF1 (0.59) | BRD9NCF1DRD2HTR1ADRD4 | |
| SCHEMBL21593838 | 0.79 | NCF1 (0.50) | BRD9NCF1DRD2HTR1ADRD4 | |
| SCHEMBL8828453 | 0.78 | DRD4 (0.46) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL27410085 | 0.78 | HTR1A (0.50) | NCF1DRD2HTR1ADRD4HTR2A | |
| SCHEMBL8828510 | 0.78 | DRD2 (0.62) | DRD2HTR1ADRD4DRD3KDM4E | |
| SCHEMBL8828437 | 0.78 | HTR1A (0.41) | SNCADRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |