Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597541 | 1.00 | LMNA (0.50) | LMNAPLGPLATCYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8597667 | 0.98 | LMNA (0.48) | LMNAPLGPLATCYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL8597672 | 0.98 | LMNA (0.48) | LMNAPLGPLATCYP2D6SLC6A2 | |
| SCHEMBL2229504 | 0.84 | PHGDH (0.43) | LMNAHSD11B1PHGDHS1PR1S1PR3 | |
| SCHEMBL1422071 | 0.80 | CES2 (0.48) | LMNAHSD11B1PHGDHS1PR1S1PR3 | |
| SCHEMBL556990 | 0.79 | ALDH1A1 (0.38) | LMNACYP2D6ALOX5HSD11B1PHGDH | |
| SCHEMBL2229500 | 0.77 | LMNA (0.38) | LMNAPLGPLATHSD11B1PHGDH | |
| SCHEMBL9001734 | 0.74 | PHGDH (0.41) | LMNAHSD11B1PHGDHS1PR1S1PR3 | |
| SCHEMBL8596855 | 0.74 | PLG (0.53) | LMNAPLGPLATCYP2D6SLC6A2 | |
| SCHEMBL8596856 | 0.74 | PLG (0.53) | LMNAPLGPLATCYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |