Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829084 | 0.83 | KLK7 (0.42) | — | |
| SCHEMBL8870576 | 0.83 | HSD17B10 (0.47) | SIGMAR1ACEKMT2A | |
| SCHEMBL8870503 | 0.83 | HSD17B10 (0.47) | SIGMAR1ACEKMT2A | |
| SCHEMBL8829146 | 0.80 | ALDH1A1 (0.40) | SIGMAR1KMT2A | |
| SCHEMBL8871032 | 0.79 | ACE (0.46) | SIGMAR1ACE | |
| SCHEMBL8829085 | 0.78 | ACE (0.45) | SIGMAR1ACE | |
| SCHEMBL8829154 | 0.78 | KMT2A (0.41) | SIGMAR1ACEKMT2A | |
| SCHEMBL8871068 | 0.77 | ACE (0.47) | SIGMAR1ACEKMT2A | |
| SCHEMBL8829203 | 0.77 | HSD17B10 (0.36) | ACE | |
| SCHEMBL8829150 | 0.76 | HSD17B10 (0.43) | SIGMAR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633270-A | Thiazolidine derivatives, preparation thereof and drugs containing samem | RHONE-POULENC RORER S.A. (FR) | 1997-05-27 | — | — | US | disclosed |