Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871032 | 0.89 | ACE (0.46) | ACEFFAR2SIGMAR1 | |
| SCHEMBL8870576 | 0.86 | HSD17B10 (0.47) | ACEFFAR2ALDH1A1POLBSIGMAR1 | |
| SCHEMBL8870503 | 0.86 | HSD17B10 (0.47) | ACEFFAR2ALDH1A1POLBSIGMAR1 | |
| SCHEMBL8871068 | 0.86 | ACE (0.47) | ACEFFAR2SIGMAR1 | |
| SCHEMBL8860462 | 0.82 | SIGMAR1 (0.39) | ACEALDH1A1POLBSIGMAR1 | |
| SCHEMBL8860452 | 0.82 | SIGMAR1 (0.39) | ACEALDH1A1POLBSIGMAR1 | |
| SCHEMBL8871931 | 0.79 | HTT (0.39) | ACEFFAR2ALDH1A1SIGMAR1 | |
| SCHEMBL8829132 | 0.78 | SIGMAR1 (0.48) | ACESIGMAR1 | |
| SCHEMBL8829187 | 0.78 | ACE (0.55) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8829192 | 0.78 | FFAR2 (0.48) | ACEFFAR2ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633270-A | Thiazolidine derivatives, preparation thereof and drugs containing samem | RHONE-POULENC RORER S.A. (FR) | 1997-05-27 | — | — | US | disclosed |