Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601168 | 0.74 | KCNH2 (0.34) | — | |
| SCHEMBL5600229 | 0.69 | KCNH2 (0.41) | — | |
| SCHEMBL9524168 | 0.69 | TDP1 (0.39) | — | |
| SCHEMBL5603649 | 0.68 | LIPG (0.34) | — | |
| SCHEMBL5601012 | 0.68 | KCNH2 (0.33) | NOS2 | |
| SCHEMBL5602241 | 0.68 | KCNH2 (0.44) | — | |
| SCHEMBL5600246 | 0.68 | KCNH2 (0.44) | — | |
| SCHEMBL150491 | 0.65 | TYR (0.40) | — | |
| SCHEMBL8829129 | 0.65 | L3MBTL1 (0.36) | — | |
| SCHEMBL8829207 | 0.65 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661158-A | HYPOTENSIVE AGENTS, ANTICHOLESTEROL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |