Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829129 | 0.73 | L3MBTL1 (0.36) | TDP1L3MBTL1 | |
| SCHEMBL9524168 | 0.71 | TDP1 (0.39) | HRH3TDP1L3MBTL1 | |
| SCHEMBL5601168 | 0.66 | KCNH2 (0.34) | TDP1L3MBTL1 | |
| SCHEMBL8829116 | 0.66 | MEN1 (0.34) | — | |
| SCHEMBL12495594 | 0.65 | L3MBTL1 (0.50) | HRH3TDP1L3MBTL1 | |
| SCHEMBL8829152 | 0.65 | NOS2 (0.30) | — | |
| SCHEMBL8829177 | 0.64 | PDE10A (0.35) | HRH3 | |
| SCHEMBL8829288 | 0.62 | NOS2 (0.37) | TDP1L3MBTL1 | |
| SCHEMBL23718261 | 0.62 | HRH3 (0.37) | HRH3TDP1L3MBTL1 | |
| SCHEMBL24072327 | 0.62 | HRH3 (0.37) | HRH3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661158-A | HYPOTENSIVE AGENTS, ANTICHOLESTEROL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0655915-A1 | USE OF ANGIOTENSIN II ANTAGONISTS FOR THE TREATMENT OF HYPERLIPIDAEME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004153-A1 | USE OF ANGIOTENSIN II ANTAGONISTS FOR THE TREATMENT OF HYPERLIPIDAEME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-03 | — | — | WO | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |