Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | FFAR2 | O15552 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860652 | 0.86 | ACE (0.56) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8870553 | 0.86 | ACE (0.56) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL11282508 | 0.85 | ACE (0.74) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL10920568 | 0.85 | ACE (0.74) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL10920564 | 0.85 | ACE (0.74) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8870611 | 0.82 | ACE (0.57) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8871782 | 0.82 | ACE (0.51) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8870565 | 0.82 | HSD17B10 (0.57) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8871013 | 0.82 | HSD17B10 (0.57) | ACEFFAR2ALDH1A1POLBHPGD | |
| SCHEMBL8829085 | 0.78 | ACE (0.45) | ACEFFAR2ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633270-A | Thiazolidine derivatives, preparation thereof and drugs containing samem | RHONE-POULENC RORER S.A. (FR) | 1997-05-27 | — | — | US | disclosed |