Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860652 | 0.90 | ACE (0.56) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL8870553 | 0.90 | ACE (0.56) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL8829187 | 0.82 | ACE (0.55) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10920568 | 0.81 | ACE (0.74) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11282508 | 0.81 | ACE (0.74) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10920564 | 0.81 | ACE (0.74) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL8871027 | 0.81 | LMNA (0.44) | ACELMNAFFAR2ALDH1A1HTT | |
| SCHEMBL8870611 | 0.81 | ACE (0.57) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL8871013 | 0.78 | HSD17B10 (0.57) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL8870565 | 0.78 | HSD17B10 (0.57) | ACELMNAFFAR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |