Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430344 | 0.88 | APAF1 (0.49) | ALDH1A1KDM4EKMT2AHPGDAPAF1 | |
| SCHEMBL8829781 | 0.88 | APAF1 (0.49) | ALDH1A1KDM4EKMT2AHPGDAPAF1 | |
| SCHEMBL8430465 | 0.83 | NPC1 (0.52) | ALDH1A1KDM4ERAB9ANPC1APAF1 | |
| SCHEMBL8829710 | 0.83 | NPC1 (0.52) | ALDH1A1KDM4ERAB9ANPC1APAF1 | |
| SCHEMBL8430466 | 0.81 | PHGDH (0.45) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8829768 | 0.81 | PHGDH (0.45) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8829775 | 0.80 | CASR (0.48) | CNR2L3MBTL1PDE2AKEAP1NFE2L2 | |
| SCHEMBL16871126 | 0.75 | KMT2A (0.51) | ALDH1A1KDM4EKMT2AHPGDAPAF1 | |
| SCHEMBL16870950 | 0.75 | KMT2A (0.51) | ALDH1A1KDM4EKMT2AHPGDAPAF1 | |
| SCHEMBL8829697 | 0.75 | CNR2 (0.49) | ALDH1A1KDM4EKMT2ACNR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608102-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENC RORER S.A. (FR) | 1997-03-04 | — | — | US | disclosed |