Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829781 | 1.00 | APAF1 (0.49) | APAF1ACP3HSD17B10LMNAMAPK1 | |
| SCHEMBL8430465 | 0.91 | NPC1 (0.52) | APAF1ACP3KDM4EKEAP1NFE2L2 | |
| SCHEMBL8829710 | 0.91 | NPC1 (0.52) | APAF1ACP3KDM4EKEAP1NFE2L2 | |
| SCHEMBL8430466 | 0.88 | PHGDH (0.45) | APAF1ACP3HSD17B10LMNAKMT2A | |
| SCHEMBL8829768 | 0.88 | PHGDH (0.45) | APAF1ACP3HSD17B10LMNAKMT2A | |
| SCHEMBL8829696 | 0.88 | ALDH1A1 (0.48) | APAF1ACP3MEN1KMT2AKDM4E | |
| SCHEMBL8829775 | 0.87 | CASR (0.48) | ACP3KEAP1NFE2L2 | |
| SCHEMBL16870950 | 0.85 | KMT2A (0.51) | APAF1ACP3HSD17B10MEN1KMT2A | |
| SCHEMBL16871126 | 0.85 | KMT2A (0.51) | APAF1ACP3HSD17B10MEN1KMT2A | |
| SCHEMBL8902251 | 0.83 | GAA (0.44) | APAF1ACP3HSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5763628-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENCE RORER S.A. (FR) | 1998-06-09 | — | — | US | disclosed |